Eva Zander Hesselkilde

PhD student, DVM.

evah@sund.ku.dk

Research Profile:

From 2013 - 2014 I was a master student within The Equine Cardiac Group where I studied the presence, expression level and cellular and regional distribution of ion channels in the equine heart.

After an externship at an Equine hospital in Finland I was granted a PhD Faculty Scholarship.

The overall aim of my PhD is to study the mechanisms of atrial fibrillation and to evaluate a new treatment principle by using the horse as an animal model. The investigation will include non-cardiac diseased horses as well as horses with both paroxysmal and persistent AF. This will make it possible to study different stages of AF development and evaluate the effect of different compounds.

Publications:

2015
Maria Mathilde Haugaard, DVM, Eva Zander Hesselkilde, DVM,* Steen Pehrson, MD, PhD, Helena Carstensen, DVM, Mette Flethøj, DVM, Kirstine Færgemand Præstegaard, DVM, Ulrik Svane Sørensen, PhD, Jonas Goldin Diness, PhD, Morten Grunnet, PhD, Rikke Buhl, DVM, PhD, Thomas Jespersen, PhD. Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses, Heart Rhythm. 2015 Apr;12(4):825-35 

Haugaard, Maria; Pehrson, Steen; Carstensen, Helena; Flethøj, Mette; Hesselkilde, Eva; Præstegaard, Kirstine; Diness, Jonas; Grunnet, Morten; Jespersen, Thomas; Buhl, Rikke. Antiarrhythmic and Electrophysiological Effects of Flecainide on Acutely Induced Atrial Fibrillation in Healthy Horses, J Vet Intern Med. 2015 Jan;29(1):339-47

2014
Eva Z Hesselkilde, Mette E Almind, Jesper Petersen, Mette Flethøj, Kirstine F Præstegaard and Rikke Buhl. Cardiac Arrhythmias and Electrolyte Disturbances in Colic Horses, Acta Vet Scand. 2014 Oct 2;56(1):58 

2013
Hesselkilde EZ, Haugaard MM, Skibsbye L, Buhl R, Jespersen T. In Vitro Characterization of the equine cardiac ion channels, European Cardiac Arrhythmia Society, 2014